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Holsti (1989:12) excludes the high-probability-of-war criterion so as to make the concept more general and applicable to non-security issues depression test health canada purchase 300 mg eskalith amex. Actions can generate threats to basic values and a high probability of war even if they are anticipated depression definition investopedia buy generic eskalith 300 mg online. At the peak of the Cuban missile crisis mood disorder lesson plan buy generic eskalith on line, President Kennedy even bypassed the Ex Com and used Robert Kennedy on back-channel negotiations with the Soviet Ambassador depression symptoms husband buy discount eskalith 300mg. Political scientists have for many years studied organizational behavior within the executive branch of the government (Simon, 1949; March and Simon, 1958), but they focused on the role of governmental politics in domestic policy, not in foreign policy. It initiated a wave of research on bureaucratic/organizational influences on foreign policy decision-making (Halperin and Kanter, 1973; Halperin, 1974; Steinbrunner, 1974: chaps. The Bureaucratic Politics and Organizational Process Models Allison (1971) drew on the organizational theory literature and developed two different but overlapping models of foreign policy that focused on the executive branch of the government. Allison contrasted these two models with "model I," which he described as "the Rational Model" but which is more accurately described as a rational unitary model of foreign policy ("model I"). Instead, the model zeros in on the inner circle of decision-makers, and assumes that if we want to understand the foreign policies made by states we need to understand who those decisionmakers are, how much power they have, and how they define their interests. One is to advise the president (or prime minister) as to the policies that will best serve the interests of the country as a whole. The other is to serve as manager of his/her organization and to act as advocate for the interests of the organization. Occasionally a key actor will be "minister without portfolio," without the responsibilities of representing a particular organization. For example, during the Cuban missile crisis President John Kennedy asked former Secretary of State Dean Acheson, who was widely respected for his expertise and judgment, to serve on the Ex Com during the Cuban missile crisis. The bureaucratic politics model posits that the policy preferences and recommendations of each of these key actors may differ because each actor may have different perceptions of the national interest and because each represents a different organization within the government, each with its own set of interests. Different organizations within the government have different tasks, and in order to effectively deal with all of the problems it 164 Decision-Making: the Organizational Level is asked to solve each organization (and sub-organization within it) generally wants to maximize the resources available to it. In addition, most organizations want to maximize their political influence, prestige, and autonomy, either as ends in themselves or as means to increase their power and resources in the future. They may also have personal interests, including career interests, their historical legacy, and business or individual financial interests. Thus the policy recommendations made to the president can reflect some combination of perception of the national interest, organizational interest, and occasionally domestic political or personal interests. This is captured by the idea that "where you stand is where you sit" (Allison and Zelikow, 1999). One common prediction, for example, is that the defense department will push for new weapons systems and for increases in the defense budget because larger defense budgets benefit the defense department and its ability to accomplish its missions. It is also frequently argued that the Department of Defense tends to be more hawkish in its policy recommendations than are other organizations. If someone has spent most of his/her career in the navy, and becomes socialized in the worldview and culture of the navy (and perhaps of a particular branch of the navy), it is not surprising that s/he might come to believe that the best interests of the country are served by having a strong navy. When an organization advocates a budgetary level or policy that serves its narrow organizational interests but perhaps not the national interest, it is sometimes difficult to tell whether that action is based on narrow self-interest or on the genuine belief that it is acting in the best interests of the country. In either case, organizational interests have an impact on policy preferences, either directly or indirectly through shaping the mindsets of organizational Decision-Making: the Organizational Level 165 actors. The first path is rationalist, while the second path involves a nonrationalist mechanism. Key bureaucratic actors vary in their political power and influence as well as their policy preferences. The influence of each actor depends on his/ her formal position in the government; control over resources, information, and policy implementation; expertise or reputation; access to the president (or prime minister); ability to mobilize external support; and political skill. The enormous budget of the Pentagon, along with its control over vital information about the potential costs, benefits, and risks inherent in the potential use of force, give it disproportionate influence on military issues. The State Department, on the other hand, has no political constituency, a smaller budget, and generally less influence (Allison and Zelikow, 1999; Halperin, 1974). The bureaucratic politics model posits a number of different actors, each with different policy preferences and positions of unequal power within the government.

Waser depression on test e cycle cheap eskalith 300 mg on-line, "Coexistence of Bipolar and Unipolar Resistive Switching Behaviors in a PtTiO2Pt Stack depression suicidal eskalith 300mg overnight delivery," Electrochemical and Solid-State Letters mood disorder vs schizophrenia purchase eskalith 300 mg on-line, vol mood disorder young children buy eskalith without a prescription. P Ma, and Y Yang, "Programmable polymer thin film and non-volatile memory device," Nature Materials, 3, 918 (2004) 127 S. Jung, "Electrical Characterization of Unipolar Organic Resistive Memory Devices Scaled Down by a Direct Metal-Transfer Method," Adv. Meskers, "Opto-electronic characterization of electron traps upon forming polymer oxide memory diodes," Appl. Blom, "Organic non-volatile memories from ferroelectric phase-separated blends," Nat. McWhorter, "Physics of the ferroelectric nonvolatile memory field effect transistor," J. Saito, "Thickness scaling of polycrystalline Pb(Zr,Ti)O3 films down to 35nm prepared by metalorganic chemical vapor deposition having good ferroelectric properties," Appl. Han, "Why is nonvolatile ferroelectric memory field-effect transistor still elusive Takahashi, "Pt/SrBi2Ta2O9/Hf-Al-O/Si field-effect-transistor with long retention using unsaturated ferroelectric polarization switching," Jap. Sakai, "Electrical properties of CaxSr1- xBi2Ta2O9 ferroelectric-gate field-effect transistors," Semicond. LeBeau, "Atomic Structure of Domain and Interphase Boundaries in Ferroelectric HfO2. Mikolajick, "Physical Mechanisms behind the FieldCycling Behavior of HfO2Based Ferroelectric Capacitors," Advanced Functional Materials 26, 4601 (2016). Bibes, "Ferroelectric tunnel junctions for information storage and processing," Nature Communications 5 (2014). Ming, "Ferroelectric-field-effect-enhanced electroresistance in metal/ferroelectric/semiconductor tunnel junctions," Nature Materials 12, 617 (2013). Triscone, "Ferroelectricity at the nanoscale: local polarization in oxide thin films and heterostructures," Science 303, 488 (2004). Grollier, "High-performance ferroelectric memory based on fully patterned tunnel junctions," Appl. Barthelemy, "Solid-state memories based on ferroelectric tunnel junctions," Nat Nano 7, 101 (2012). Dai, "Nanoscale ferroelectric tunnel junctions based on ultrathin BaTiO3 film and Ag nanoelectrodes," Applied Physics Letters 101, 142905 (2012). Kim, "Towards the limit of ferroelectric nanostructures: switchable sub-10 nm nanoisland arrays," J. Sefrioui, "Resonant electron tunneling assisted by charged domain walls in multiferroic tunnel junctions," Nature Nanotechnology 12, 655 (2017). Nagarajan, "Method to distinguish ferroelectric from nonferroelectric origin in case of resistive switching in ferroelectric capacitors," Applied Physics Letters 92, 62907 (2008). Nagaosa, "Interfaces of Correlated Electron Systems: Proposed Mechanism for Colossal Electroresistance," Phys. Tokura, "Current switching of resistive states in magnetoresistive manganites," Nature 388 (1997) 50 191 S. Ignatiev, "Electric-pulse-induced reversible resistance change effect in magnetoresistive films," Appl. Tokura, "Hysteretic current-voltage characteristics and resistance switching at a rectifying Ti/Pr0. Ramanathan, "Electrical triggering of metal-insulator transition in nanoscale vanadium oxide junctions," J.

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Subunit vaccines In the recent decades depression symptoms memory problems discount eskalith 300mg visa, subunit vaccines are becoming promising vaccine candidates against Brucella infection due to their safety profile depression definition biology order eskalith overnight. The major advantages of subunit vaccines over live vaccines is that subunit vaccines eliminate safety concerns associated with depression glass buy 300 mg eskalith visa, they are less biohazardous depression symptoms heart pain purchase eskalith 300 mg with mastercard, well defined, avirulent, noninfectious, and nonviable. However, subunit vaccines cannot replicate the immunogenicity of live vaccines and thus, they are not as effective as live attenuated vaccines. In order to develop a new effective Brucella vaccine, selection of an immunogen with potential to induce an adequate immune responses (biased towards a Th1) and confer the high level of protection is essential[4,58]. However, only a few immunogens have demonstrated significant protective efficacy, in vivo. The first world report on the evaluation of the protective efficacy of the 36 kDa outer membrane protein 2b (Omp2b) antigen and its truncated form has been performed by Golshani et al. Using immunoinformatics algorithms, mapping potential Tand B-cell epitopes are promising approaches to design new vaccine candidates. Furthermore, the numbers of immunogens have been analyzed using bioinformatics tools to design new vaccine targets based on epitope mapping [66-72]. All parts of Iran are endemic for brucellosis, and it causes high economic loss due to livestock abortion and has serious public health consequences. Brucellosis has been an occupational risk for people having contact with infected animals, and nonoccupational source of the disease includes consumption of fresh and unpasteurized dairy products. Vast immunization of livestock is the most preventive program in the endemic countries like Iran; however, due to the major limitations of the current commercial available vaccines and the lack of the human vaccine, finding a new protective and safe vaccine target seems to be essential. The corps disease: Brucellosis and its historical association with the royal army medical corps. The genome sequence of the facultative intracellular pathogen Brucella melitensis. Characterization of novel Brucella strains originating from wild native rodent species in North Queensland, Australia. Identification at Biovar level of Brucella isolates causing abortion in small ruminants of Iran. Khazaei S, Shojaeian M, Zamani R, Mansori K, Mohammadian-Hafshejani A, Rezaeian-Langroodi R, Ayubi E, Khazaei Z. Epidemiological survey of brucellosis in human and animals in Birjand, East of Iran. Seroprevalence of brucellosis and risk factors related to high risk occupational groups in Kazeroon, South of Iran. The prevalence of Brucella abortus and Brucella melitensis in local cheese produced in Sarab city, Iran and its public health implication. Brucellosis: Prevalence and retrospective evaluation of risk factors in western cities of Tehran province, Iran. Epidemiological features and clinical manifestations in 469 adult patients with brucellosis in Babol, Northern Iran. Biological risks and laboratory-acquired infections: A reality that cannot be ignored in health biotechnology. Brucellosis: review on the recent trends in pathogenicity and laboratory diagnosis. Evaluation of conventional Castaneda and lysis centrifugation blood culture techniques for diagnosis of human brucellosis. Hajia M, Fallah F, Angoti G, Karimi A, Rahbar M, Gachkar L, Mokhtari B, Sanaei A, Rastegar Lari A. Epidemiological, clinical and para clinical aspects of brucellosis in Imam Khomeini and Sina hospitals of Tehran (1998-2009). Recent advances in understanding immunity against brucellosis: application for vaccine development. Control and eradication program for bovine brucellosis in Iran: An epidemiological survey. Subcutaneous immunization with a novel immunogenic candidate (urease) confers protection against Brucella abortus and Brucella melitensis infections. Acta pathologica, microbiologica, et immunologica Scandinavica 2015; 123(8):667-675. Immunization of mice with a novel recombinant molecular chaperonconfers protection against Brucella melitensis infection. Identification of a new immunogenic candidate conferring protection against Brucella melitensis infection in mice.

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In other regime types anxiety medications order 300mg eskalith with amex, especially democratic regimes depression verses cheap 300mg eskalith free shipping, it is more cautious individuals who avoid alienating key constituencies that are the ones more likely to end up on top depression diet order eskalith in united states online. Propensities toward taking risks are also a function of the situation key depression test software download quality 300 mg eskalith, as suggested by prospect theory, which we discuss later in this chapter. Decision-Making: the Individual Level 139 Beliefs and images Individual political leaders vary widely in their personalities and belief systems, and those variations help to explain different perceptions of threats and opportunities in the international system. Beliefs are particularly important because they have a significant impact on how an individual perceives and interprets information about the adversary and about the world more generally. As we note in a subsequent section, how an individual perceives threats in a particular situation is influenced as much or more by his/her prior beliefs about the adversary and about world politics in general as by the current details of a particular situation (Jervis, 1976). There is no consensus among scholars as to the most useful way to classify the wide variety of individual beliefs. The former include questions about the fundamental nature of politics and conflict, the extent to which political outcomes are predictable or subject to chance, and the ability of political leaders to influence the flow of events. Instrumental beliefs include ideas about optimal strategies for achieving political ends, issues of timing, and conceptions of risk. Are wars usually the result of the deliberate actions of states that prefer war to peace, or are they inadvertent, resulting from an unwanted and unexpected process of escalation Images of optimal bargaining strategies 140 Decision-Making: the Individual Level include beliefs about the relative efficacy of coercive and more conciliatory bargaining strategies. These include beliefs about whether coercive threats induce compliance or whether they provoke counter-threats and escalation, and also beliefs about the proper timing and mix of coercive and accommodative strategies. Kennedy believed that the sequencing of coercive and conciliatory behavior was critical in achieving his objectives. Kennedy feared that a purely diplomatic strategy without coercive threats would have been more likely to escalate to risky military action (George, 1994). The emphasis on images of the adversary can also be found in other lines of work that goes back to the 1960s. Finlay, Holsti, and Fagan (1967) wrote Enemies in Politics and White (1968) emphasized the importance of both adversary images (the "diabolical enemy image") and self-images, including the "virile self-image" and the "moral self-image. We next turn to a more general discussion of factors affecting threat perception in the international system. The psychology of threat perception the perception and misperception of threat is shaped by causal variables at all levels of analysis. Decision-Making: the Individual Level 141 this problem is compounded if the adversary engages in "strategic deception" to conceal its intentions. Bureaucratic politics and organizational processes, which we discuss in the next chapter, play an important role in shaping what information gets processed and passed on to top decisionmakers, and who gets to see that information. Societal cultures, ideologies, and religions introduce an additional level of conceptual filters. It is individuals in high-level decision-making groups whose judgments about threats and opportunities determine the actual decisions for war and peace, however, and we focus here on the individual psychology of threat perception. Cognitive biases reflect the way the brain is "hard-wired" to process information quite independently of the impact of human emotions and motivations. The basic premise of the "cognitive" perspective is that the world is extraordinarily complex, incoherent, and changing, while people have limited information processing capabilities to comprehend that world. People try to act rationally, but they face many obstacles in approaching the ideal-type rationality described earlier in this chapter. In order to make sense of a complex and uncertain world, people adopt a number of cognitive shortcuts or heuristics (which we illustrate below) that help to simplify that world and make it more understandable. Although the use of some kind of simplifying heuristics is necessary to make sense of the external world, these heuristics can generate some important cognitive distortions (Tversky and Kahneman, 1974; Nisbett and Ross, 1980). In contrast to cognitive biases, motivated biases derive from the emotional side of human beings, from their psychological needs, fears, guilt, and desires (Janis and Mann, 1977).

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